Premenopausal Breast Cancer: Exercise and Leukocyte Telomere Length
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چکیده
منابع مشابه
Is Leukocyte Telomere Length Related with Lung Cancer Risk?: A Meta-Analysis
Background: Epidemiological studies have probed the correlation between telomere length and the risk of lung cancer, but their findings are inconsistent in this regard. The present meta-analysis study has been carried out to demonstrate the association between relative telomere length in peripheral blood leukocytes and the risk of lung cancer using an established Q-PCR technique. Methods:...
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In culture, replicating human somatic cells display progressive telomere shortening. Ultimately, such cells either undergo apoptosis or enter a state of replicative senescence that is triggered by critically shortened telomeres. Accordingly, telomere length is an index of both the replicative history and the replicative potential of human somatic cells in culture (1). Most replicating human som...
متن کاملTelomere length in peripheral leukocyte DNA and gastric cancer risk.
Telomere length reflects lifetime cumulative oxidative stress from environmental exposures, such as cigarette smoking and chronic inflammation. Shortened telomere length is thought to cause genomic instability and has been associated with several cancers. We examined the association of telomere length in peripheral leukocyte DNA with gastric cancer risk as well as potential confounding factors ...
متن کاملLeukocyte Telomere Length and Cancer Risk: A Dynamic Problem
Telomeres are the protective structure at both ends of each chromoThe decelerating age-adjusted LTL attrition in cancer cases as they some. Telomere length is widely considered a marker of biological aging. For convenience, telomere lengths in human population studies have been predominately measured in peripheral blood leukocytes. Although leukocyte telomere length (LTL) is generally inversely...
متن کاملChange in peripheral blood leukocyte telomere length and mortality in breast cancer survivors.
BACKGROUND Progressive telomere shortening with cell division is a hallmark of aging. Short telomeres are associated with increased cancer risk, but there are conflicting reports about telomere length and mortality in breast cancer survivors. METHODS We measured peripheral blood leukocyte telomere length at two time points in women enrolled in a multiethnic, prospective cohort of stage I to s...
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ژورنال
عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention
سال: 2017
ISSN: 1055-9965,1538-7755
DOI: 10.1158/1055-9965.epi-17-0037